science
Product information
Ingredients
Cocoa mass (min 70%) cocoa butter, chicory root fiber, corn fiber, emulsifier: sunflower lecithin, vanilla extract, Bio Astaxanthin, vanilla powder, lime, acidulant: citric acid, salt
Free from palm oil, gluten, soy lecithin and other allergens
Research and studies
CACAO
- Dried Chicory Root Improves Bowel Function, Benefits Intestinal Microbial Trophic Chains and Increases Faecal and Circulating Short Chain Fatty Acids in Subjects At Risk for Type 2 Diabetes
- The Health Effects of Chocolate and Cocoa: A Systematic Review
- Impact of cocoa flavanols on human health
- Bioactives in Cocoa: Novel Findings, Health Benefits, and Extraction Techniques
- Cocoa and Chocolate their clinical
benefits: Insights in study design - Cocoa shown to reduce blood pressure and arterial stiffness in first real-life study
- Cocoa shown to reduce blood pressure and arterial stiffness in first real-life study
- Cocoa and Cardiovascular Health
CHICORY FIBER
- Chicory: Understanding the Effects and Effectors of This Functional Food
- Back to the Roots: Revisiting the Use of the Fiber-Rich Cichorium intybus L. Taproots
- Are There Health Benefits of Chicory?
- Chicory root fibre increases good gut bacteria regardless of food application, research asserts
- Chicory root flour – A functional food with potential multiple health benefits evaluated in a mice model
- Dried Chicory Root Improves Bowel Function, Benefits Intestinal Microbial Trophic Chains and Increases Faecal and Circulating Short Chain Fatty Acids in Subjects At Risk for Type 2 Diabetes
BRAIN
Neurological Diseases
- The Use of Antioxidants in the Treatment of Migraine – PMC (nih.gov)
- Marine algae as emerging therapeutic alternatives for depression: A review – PMC (nih.gov)
- The Impact of Systemic Inflammation on Neurodevelopment – PMC (nih.gov)
- Inflammation and Brain Health | Harvard Medicine magazine
- Astaxanthin Antitumor Effect – LKT Labs
- Effects of astaxanthin-rich Haematococcus pluvialis extract on cognitive function: a randomised, double-blind, placebo-controlled study – PubMed (nih.gov)
- Effect of Astaxanthin Supplementation on Psychophysiological Heart-Brain Axis Dynamics in Healthy Subjects | Talbott | Functional Foods in Health and Disease (ffhdj.com)
- Oxidative Stress and Immune System Dysfunction in Autism Spectrum Disorders – PubMed (nih.gov)
- Natural Antioxidants: A Novel Therapeutic Approach to Autism Spectrum Disorders? – PMC (nih.gov)
- On the Neuroprotective Role of Astaxanthin: New Perspectives? – PMC (nih.gov)
- Astaxanthin May Help Improve Overall Mood and Cognitive Function (naturecity.com)
- Healthy aging and astaxanthin (naturalproductsinsider.com)
- Role of oxidative stress in Alzheimer’s disease – PubMed (nih.gov)
- Antitumour Effects of Astaxanthin and Adonixanthin on Glioblastoma – PubMed (nih.gov)
- Astaxanthin improves cognitive performance in mice following mild traumatic brain injury – PubMed (nih.gov)
- Effects of astaxanthin on depressive and sleep symptoms: A narrative mini-review – PMC (nih.gov)
EYESIGHT
Eye Diseases
SPORT
- The astaxanthin-induced improvement in lipid metabolism during exercise is mediated by a PGC-1α increase in skeletal muscle – PubMed (nih.gov)
- Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E – PubMed (nih.gov)
- Astaxanthin for Sports & Fitness – Health Information Library | PeaceHealth
- Effect of astaxanthin and exercise on antioxidant capacity of human body, blood lactic acid and blood uric acid metabolism – ScienceDirect
- Astaxanthin limits exercise-induced skeletal and cardiac muscle damage in mice – PubMed (nih.gov)
- Effect of astaxanthin on cycling time trial performance – PubMed (nih.gov)
- Effects of Dietary Supplementation of Astaxanthin and Sesamin on Daily Fatigue: A Randomized, Double-Blind, Placebo-Controlled, Two-Way Crossover Study – PubMed (nih.gov)
- Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans – PubMed (nih.gov)
- Effects of astaxanthin on oxidative stress in overweight and obese adults – PubMed (nih.gov)
- Free Radicals, Antioxidants in Disease and Health – PMC (nih.gov)
- Alcohol, oxidative stress, and free radical damage – PubMed (nih.gov)
- Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis – PubMed (nih.gov)
- Marine Bioactives and Potential Application in Sports – PMC (nih.gov)
LUNGS
Pulmonary System
- The Promising Effects of Astaxanthin on Lung Diseases – PubMed (nih.gov)
- A dietary carotenoid reduces immunopathology and enhances longevity through an immune depressive effect in an insect model – PubMed (nih.gov)
- Potential of natural astaxanthin in alleviating the risk of cytokine storm in COVID-19 – PubMed (nih.gov)
- Astaxanthin protective barrier and its ability to improve the health in patients with COVID-19 – PubMed (nih.gov)
- The Protective Effects of Astaxanthin on the OVA-Induced Asthma Mice Model – PMC (nih.gov)
- Epidemiologic evidence linking oxidative stress and pulmonary function in healthy populations – PMC (nih.gov)
- Cystic Fibrosis – Treatment | NHLBI, NIH
- Thyroid Hormones and Antioxidant Systems: Focus on Oxidative Stress in Cardiovascular and Pulmonary Diseases – PMC (nih.gov)
CANCER
- Antitumor activity of astaxanthin and its mode of action – PubMed (nih.gov)
- A comparison of the anticancer activities of dietary beta-carotene, canthaxanthin and astaxanthin in mice in vivo – PubMed (nih.gov)
- Effects of Astaxanthin on the Proliferation and Migration of Breast Cancer Cells In Vitro – PMC (nih.gov)
- Contribution of the antioxidative property of astaxanthin to its protective effect on the promotion of cancer metastasis in mice treated with restraint stress – ScienceDirect
- Cancers | Free Full-Text | Carotenoids in Cancer Apoptosis—The Road from Bench to Bedside and Back (mdpi.com)
- Astaxanthin anticancer effects are mediated through multiple molecular mechanisms: A systematic review – ScienceDirect
- New Research on Astaxanthin and Cancer – – Life Extension
- Is it a cure for cancer and more? – The Times Gazette
- Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans – PubMed (nih.gov)
- C-Reactive Protein and Breast Cancer: New Insights from Old Molecule – PubMed (nih.gov)
- Multiple Mechanisms of Anti-Cancer Effects Exerted by Astaxanthin – PMC (nih.gov)
- Could we use antioxidants during cancer chemotherapy or not? | Request PDF (researchgate.net)
- STEAP1 Is Associated with the Invasive and Oxidative Stress Phenotype of Ewing Tumors | Molecular Cancer Research | American Association for Cancer Research (aacrjournals.org)
- Do We Utilize Our Knowledge of the Skin Protective Effects of Carotenoids Enough? – PubMed (nih.gov)
- The Role of the Reactive Oxygen Species Scavenger Agent, Astaxanthin, in the Protection of Cisplatin-Treated Patients Against Hearing Loss – PMC (nih.gov)
- Multiple Mechanisms of Anti-Cancer Effects Exerted by Astaxanthin – PMC (nih.gov)
- Astaxanthin Prevents Human Papillomavirus L1 Protein Binding in Human Sperm Membranes – PMC (nih.gov)
- Antioxidants and other nutrients do not interfere with chemotherapy or radiation therapy and can increase kill and increase survival, part 1 – PubMed (nih.gov)
- Antioxidants as precision weapons in war against cancer chemotherapy induced toxicity – Exploring the armoury of obscurity – PubMed (nih.gov)
- Antioxidants as precision weapons in war against cancer chemotherapy induced toxicity – Exploring the armoury of obscurity – PMC (nih.gov)
- STEAP1 is associated with the invasive and oxidative stress phenotype of Ewing tumors – PubMed (nih.gov)
- Antitumour Effects of Astaxanthin and Adonixanthin on Glioblastoma – PubMed (nih.gov)
- Effects of Astaxanthin on the Proliferation and Migration of Breast Cancer Cells In Vitro – PubMed (nih.gov)
- The Promising Effects of Astaxanthin on Lung Diseases – PubMed (nih.gov)
- Anti-Tumor Effects of Astaxanthin by Inhibition of the Expression of STAT3 in Prostate Cancer – PMC (nih.gov)
- Structural and Functional Characterization of Aromatase, Estrogen Receptor, and Their Genes in Endocrine-Responsive and – Resistant Breast Cancer Cells – PMC (nih.gov)
- Do We Utilize Our Knowledge of the Skin Protective Effects of Carotenoids Enough? – PubMed (nih.gov)
- Continuous astaxanthin intake reduces oxidative stress and reverses age-related morphological changes of residual skin surface components in middle-aged volunteers – PubMed (nih.gov)
- The conundrum of dietary antioxidants in cancer chemotherapy – PubMed (nih.gov)
- US Patent for Method of inhibiting aromatase with specific dietary supplements Patent (Patent # 7,731,992 issued June 8, 2010) – Justia Patents Search
- Antioxidants | Free Full-Text | Antiangiogenic Phytochemicals Constituent of Diet as Promising Candidates for Chemoprevention of Cancer (mdpi.com)
- Astaxanthin suppresses the metastasis of colon cancer by inhibiting the MYC-mediated downregulation of microRNA-29a-3p and microRNA-200a – PMC (nih.gov)
- Antioxidants and Therapeutic Targets in Ovarian Clear Cell Carcinoma – PMC (nih.gov)
SKIN
Integumentary (Skin) System
- Efficacy of Astaxanthin for the Treatment of Atopic Dermatitis in a Murine Model – PMC (nih.gov)
- Eczema (Atopic Dermatitis) | NIH: National Institute of Allergy and Infectious Diseases
- Protective effects of astaxanthin on skin deterioration – PubMed (nih.gov)
- Effect of astaxanthin on cutaneous wound healing – PMC (nih.gov)
- Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review – PMC (nih.gov)
- Healthy aging and astaxantin (naturalproductsinsider.com)
- The Protective Role of Astaxanthin for UV-Induced Skin Deterioration in Healthy People—A Randomized, Double-Blind, Placebo-Controlled Trial – PMC (nih.gov)
- Influence of equol and resveratrol supplementation on health-related quality of life in menopausal women: A randomized, placebo-controlled study – PubMed (nih.gov)
- Cytoprotective Effects of Citicoline and Homotaurine against Glutamate and High Glucose Neurotoxicity in Primary Cultured Retinal Cells – PubMed (nih.gov)
- Synergistic effect of L-Carnosine and EGCG in the prevention of physiological brain aging – PubMed (nih.gov)
- Enhancement of mitochondrial biogenesis with polyphenols: combined effects of resveratrol and equol in human endothelial cells – PubMed (nih.gov)
- Nutrition and enhancing youthful-appearing skin – PubMed (nih.gov)
- A new view concerning the effects of collagen hydrolysate intake on skin properties – PubMed (nih.gov)
- Rosacea, Reactive Oxygen Species, and Azelaic Acid – PMC (nih.gov)
LIVER
- Astaxanthin improves glucose metabolism and reduces blood pressure in patients with type 2 diabetes mellitus – PubMed (nih.gov)
- Prevention of diabetic nephropathy by treatment with astaxanthin in diabetic db/db mice – PubMed (nih.gov)
- Marine Drugs | Free Full-Text | Impact of Astaxanthin on Diabetes Pathogenesis and Chronic Complications (mdpi.com)
- Astaxanthin Prevents Alcoholic Fatty Liver Disease by Modulating Mouse Gut Microbiota – PubMed (nih.gov)
- Astaxanthin and its Effects in Inflammatory Responses and Inflammation-Associated Diseases: Recent Advances and Future Directions – PubMed (nih.gov)
- Protective effects of astaxanthin on ConA-induced autoimmune hepatitis by the JNK/p-JNK pathway-mediated inhibition of autophagy and apoptosis – PubMed (nih.gov)
- Astaxanthin in Liver Health and Disease: A Potential Therapeutic Agent – PubMed (nih.gov)
- Astaxanthin attenuates hepatic damage and mitochondrial dysfunction in non-alcoholic fatty liver disease by up-regulating the FGF21/PGC-1α pathway – PubMed (nih.gov)
- The Beneficial Effects of Astaxanthin on Glucose Metabolism and Modified Low-Density Lipoprotein in Healthy Volunteers and Subjects with Prediabetes – PMC (nih.gov)
- The Protective Effect of Astaxanthin on Cognitive Function via Inhibition of Oxidative Stress and Inflammation in the Brains of Chronic T2DM Rats – PubMed (nih.gov)
- Astaxanthin: A Potential Mitochondrial-Targeted Antioxidant Treatment in Diseases and with Aging – PMC (nih.gov)
- Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E – PubMed (nih.gov)
- Effects of astaxanthin on oxidative stress in overweight and obese adults – PubMed (nih.gov)
- An Intimate Relationship between ROS and Insulin Signalling: Implications for Antioxidant Treatment of Fatty Liver Disease – PubMed (nih.gov)
- Free Radicals, Antioxidants in Disease and Health – PMC (nih.gov)
- Alcohol, oxidative stress, and free radical damage – PubMed (nih.gov)
- Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis – PubMed (nih.gov)
- Impact of Astaxanthin on Diabetes Pathogenesis and Chronic Complications – PMC (nih.gov)
- Astaxanthin Attenuates Hypertensive Vascular Remodeling by Protecting Vascular Smooth Muscle Cells from Oxidative Stress-Induced Mitochondrial Dysfunction (hindawi.com)
STOMACH
Gastrointestinal Disorders
- Astaxanthin and β-carotene in Helicobacter pylori-induced Gastric Inflammation: A Mini-review on Action Mechanisms – PubMed (nih.gov)
- Transcriptome Analysis of the Inhibitory Effect of Astaxanthin on Helicobacter pylori-Induced Gastric Carcinoma Cell Motility – PMC (nih.gov)
- Dietary astaxanthin inhibits colitis and colitis-associated colon carcinogenesis in mice via modulation of the inflammatory cytokines – PubMed (nih.gov)
- Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications—A Review – PMC (nih.gov)
- Astaxanthin, a xanthophyll carotenoid, prevents development of dextran sulphate sodium-induced murine colitis – PMC (nih.gov)
- Dietary astaxanthin inhibits colitis and colitis-associated colon carcinogenesis in mice via modulation of the inflammatory cytokines – ScienceDirect
- Anti-Oxidant and Anti-Inflammatory Effects of Astaxanthin on Gastrointestinal Diseases – PMC (nih.gov)
CHOLESTEROL
Cardiovascular System
- Astaxanthin and its Effects in Inflammatory Responses and Inflammation-Associated Diseases: Recent Advances and Future Directions – PMC (nih.gov)
- Antioxidant and anti-inflammatory mechanisms of action of astaxanthin in cardiovascular diseases (Review) – PMC (nih.gov)
- Is the Heart a Muscle? Anatomy, Heart Conditions, and More (healthline.com)
- Arteries of the Body: Picture, Anatomy, Definition & More (healthline.com)
- Venous System: Vein Anatomy and Function, Vein Types, Conditions (healthline.com)
- Antioxidants | Free Full-Text | Oxidative Stress in Cardiovascular Diseases (mdpi.com)
- Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects – PubMed (nih.gov)
- Potential Anti-Atherosclerotic Properties of Astaxanthin – PubMed (nih.gov)
- Marine Carotenoids and Cardiovascular Risk Markers – PMC (nih.gov)
- Impact of astaxanthin supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials – ScienceDirect
- Astaxanthin: A Novel Potential Treatment for Oxidative Stress and Inflammation in Cardiovascular Disease – American Journal of Cardiology (ajconline.org)
- New Study Investigates the Effects of Astaxanthin on Cardiac Function in Patients with Heart Failure (designsforhealth.com)
- Effects of 3-Month Astaxanthin Supplementation on Cardiac Function in Heart Failure Patients with Left Ventricular Systolic Dysfunction-A Pilot Study – PMC (nih.gov)
- Free Radicals, Antioxidants in Disease and Health – PMC (nih.gov)
- Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis – PubMed (nih.gov)
- Healthy aging and astaxantin (naturalproductsinsider.com)
- Alcohol, oxidative stress, and free radical damage – PubMed (nih.gov)
- Antihypertensive effects of astaxanthin – PubMed (nih.gov)
- What to Know About Peripheral Arterial Disease (PAD) (healthline.com)
- Preventive treatment of astaxanthin provides neuroprotection through suppression of reactive oxygen species and activation of antioxidant defense pathway after stroke in rats – PubMed (nih.gov)
- Astaxanthin Attenuates Hypertensive Vascular Remodeling by Protecting Vascular Smooth Muscle Cells from Oxidative Stress-Induced Mitochondrial Dysfunction (hindawi.com)
- Chronic Diseases in America (cdc.gov)
- Thyroid Hormones and Antioxidant Systems: Focus on Oxidative Stress in Cardiovascular and Pulmonary Diseases – PMC (nih.gov)
INFLAMMATION
Bone and Joint
- Suppression Effect of Astaxanthin on Osteoclast Formation In Vitro and Bone Loss In Vivo – PubMed (nih.gov)
- Astaxanthin attenuates irradiation-induced osteoporosis in mice by inhibiting oxidative stress, osteocyte senescence, and SASP – Food & Function (RSC Publishing)
- Antioxidant Intake and Risks of Rheumatoid Arthritis and Systemic Lupus Erythematosus in Women – PMC (nih.gov)
REPRODUCTIVE SYSTEM
- Astaxanthin ameliorates inflammation, oxidative stress, and reproductive outcomes in endometriosis patients undergoing assisted reproduction: A randomized, triple-blind placebo-controlled clinical trial – PMC (nih.gov)
- Ginsenoside Rg1 and astaxanthin act on the hypothalamus to protect female mice against reproductive aging – PMC (nih.gov)
- Safety assessment of astaxanthin from Haematococcus pluvialis: Acute toxicity, genotoxicity, distribution and repeat-dose toxicity studies in gestation mice – PubMed (nih.gov)
- Effect of Astaxanthin on Human Sperm Capacitation – PMC (nih.gov)
- Inhibitory Effect of Astaxanthin on Testosterone-Induced Benign Prostatic Hyperplasia in Rats – PubMed (nih.gov)
- Health Effects of Carotenoids during Pregnancy and Lactation – PMC (nih.gov)
- Astaxanthin improves the development of the follicles and oocytes through alleviating oxidative stress induced by BPA in cultured follicles – PMC (nih.gov)
- US Patent for Method of inhibiting aromatase with specific dietary supplements Patent (Patent # 7,731,992 issued June 8, 2010) – Justia Patents Search
- Structural and Functional Characterization of Aromatase, Estrogen Receptor, and Their Genes in Endocrine-Responsive and – Resistant Breast Cancer Cells – PMC (nih.gov)
- Reactive oxygen species and male reproductive hormones | Reproductive Biology and Endocrinology | Full Text (biomedcentral.com)
ROS (Reactive Oxygen Species)
- Free Radicals, Antioxidants in Disease and Health – PMC (nih.gov)
- Alcohol, Oxidative Stress, and Free Radical Damage (nih.gov)
- Role of Reactive Oxygen Species in the Progression of Type 2 Diabetes and Atherosclerosis (hindawi.com)
- Algalif_Natural-Astaxanthin_Review-of-Human-Clinical-Studies-_0917_web.pdf
- Free Radicals: How They Affect Your Body – Cleveland Clinic
- Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review – PMC (nih.gov)
- Astaxanthin protects oxidative stress mediated DNA damage and enhances longevity in Saccharomyces cerevisiae – PubMed (nih.gov)
- Structures of Astaxanthin and Their Consequences for Therapeutic Application (hindawi.com)
- Pictures: Signs of Chronic Inflammation You May Not Expect (webmd.com)
- Thyroid Hormones and Antioxidant Systems: Focus on Oxidative Stress in Cardiovascular and Pulmonary Diseases – PMC (nih.gov)
- Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans – PMC (nih.gov)